isolation of phenolic derivatives and essential oil analysis of prangos ferulacea (l.) lindl. aerial parts

نویسندگان

maryam soleimani department of pharmacognosy, faculty of pharmacy and medicinal plant research center, tehran university of medical sciences, tehran, iran.

abbas hadjiakhoondi department of pharmacognosy, faculty of pharmacy and medicinal plant research center, tehran university of medical sciences, tehran, iran.

narguess yassa tehran univ. med. sci.

چکیده

prangos ferulacea (l.) lindl. (apiaceae) is a medicinal plant distributed in mediterranean regions, caucasia and southwest of asia. in the present study phytochemical constituents of the extract obtained from the aerial parts of p. ferulacea were investigated using various chromatographic and spectroscopic methods. essential oil of the plant aerial parts was also analyzed using gc-ms. five phenolic derivatives, isoimperatorin (1), ferudenol (2), caffeic acid glucosyl ester (3), isorhamnetin-3-o-β-d-glucopyranoside (4) and quercetin-3-o-β-d-glucopyranoside (5) were isolated from the aerial parts of p. ferulacea and their structures were elucidated using 1h-nmr, 13c-nmr, ei-ms and uv spectral analyses. twenty seven compounds were also identified in the essential oil of plant aerial parts, of which β-pinene (43.1%), α-pinene (22.1%) and -δ3-carene (16.9%) were characterized as main compounds. the results of this study introduce p. ferulacea as a source of potentially bioactive phenolic compounds and suggest it as an appropriate candidate for further studies.

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Isolation of Phenolic Derivatives and Essential Oil Analysis of Prangos ferulacea (L.) Lindl. Aerial Parts

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عنوان ژورنال:
the iranian journal of pharmaceutical research

جلد ۱۶، شماره Special Issue، صفحات ۲۰۷-۲۱۵

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